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Ocean Optics
Worldwide Headquarters
Largo, Florida, USA

+1 727-733-2447

info@oceanoptics.com

Sales, Service
& Support Facility
Duiven, The Netherlands

+31 26-319-0500

info@oceanoptics.eu

Ocean Optics GmbH Sales,
Service & Support Facility
Ostfildern, Germany

+49 711-34-16-96-0

info@oceanoptics.eu

Sales Support
for the
United Kingdom

+44 1865-811118

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Sales, Service
& Support Facilities
Shanghai, PRC – Beijing, PRC

+86 21-6295-6600

asiasales@oceanoptics.com

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Home > Frequently Asked Questions > Products > Accessories > What chemicals can be detected with Ocean Optics SERS substrates, and at what concentrations?

What chemicals can be detected with Ocean Optics SERS substrates, and at what concentrations?

We have tested a wide variety of analytes with our SERS substrates using a QE Pro-Raman spectrometer and 785 nm probe, as shown in the table below. The lowest concentration measured is also shown, but will vary with the sensitivity of the Raman instrument used for measurement.

Analyte Classification SERS Active Substrate Lowest detectable concentration

Explosives

TNT Explosive Yes 10 ppm
RDX Explosive No NA
PETN Explosive No NA

Pharmaceuticals and Illicit Drugs

Cocaine Illict drug Yes 340 ppm
THC Illict drug (Cannabis) Yes 3000 ppm
2-propranolol Beta blocker Yes 30 ppm
Triamterene Diuretic Yes 250 ppm
Ipratropium bromide Bronchodilator Weakly 4000 ppm
Nicotinamide B vitamin Yes 12 ppm
MDMA Illict drug (Extasy) Weakly Not measured
EDDP Illict drug Weakly Not measured
Ketamine Pain killer Weakly Not measured
Carbamazepine Anticonvulsant Weakly Not measured
4-fluoroamphetamine Designer drug (stimulant) No NA
Amphetamine sulphate Illicit drug (Speed) No NA
JWH-018 (1-pentyl-3-(1-naphthoyl)indole) Analgesic (used in synthetic canabbinoids) No NA
4-MMC (Mephedrone) Synthetic stimulant drug No NA
Methaphethamine Central nervous system stimulant drug No NA
2-phenylacetoacetonitrile Starting material for illicit drug synthesis No NA
Nicotinic acid B vitamin Weakly Not measured
Riboflavin B vitamin Weakly Not measured
Pyridoxine B vitamin Weakly Not measured
Nifedipine Calcium channel blocker drug Weakly Not measured

Food & Agriculture

Crystal violet Fungicide Yes 4 ppb
Malachite green Fungicide Yes 4 ppb
Thiram Fungicide, ectoparasiticide, and animal repellent Yes 1 ppm
Phosmet Organophosphate insecticide Yes 1 ppm
Malathion Organophosphate insecticide Yes 1 ppm
Melamine Food adulterant Yes 10 ppm
Enrofloxacin Antibiotic used in farming No NA
Cyanuric acid Metabolite of food adulterant melamine Yes 1000 ppm

Taggants & Markers

1,2-bis(4-pyridyl)ethylene  (BPE) Taggant / Marker Yes 0.2 ppb
4-mercaptobenzoic acid Taggant / Marker Yes 15 ppb
4-mercaptopyridine Taggant / Marker Yes 0.1 ppm
2-naphthalenethiol Taggant / Marker Yes 0.2 ppm
1,10-phenantroline Taggant / Marker Yes 0.2 ppm
1,2-Bis(4-pyridyl)ethane (BPYE) Taggant / Marker Yes 18 ppm
4,4’-Trimethylenedipyridine (TMDP) Taggant / Marker Yes 20 ppm
1,4-Diethynylbenzene (DEB) Taggant / Marker Yes 13 ppb

*Note: Data last updated November 2015.

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